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The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor
The GABA(B) receptor is well recognized as being composed of two subunits, GABA(B1) and GABA(B2). Both subunits share structural homology with other class-III G protein-coupled receptors (GPCRs). They are composed of two main domains, a heptahelical domain (HD) typical of all GPCRs and a large extra...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2557059/ https://ncbi.nlm.nih.gov/pubmed/15126507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M400930200 |
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