The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

The GABA(B) receptor is well recognized as being composed of two subunits, GABA(B1) and GABA(B2). Both subunits share structural homology with other class-III G protein-coupled receptors (GPCRs). They are composed of two main domains, a heptahelical domain (HD) typical of all GPCRs and a large extra...

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Autors principals: Binet, Virginie, Brajon, Carole, Le Corre, Laurent, Acher, Francine, Pin, Jean-Philippe, Prézeau, Laurent
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557059/
https://ncbi.nlm.nih.gov/pubmed/15126507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M400930200
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