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Quantitation of Acrolein-Derived 3-Hydroxypropylmercapturic Acid in Human Urine by Liquid Chromatography-Atmospheric Pressure Chemical Ionization-Tandem Mass Spectrometry: Effects of Cigarette Smoking
Recently published data suggest that acrolein (1), a toxic but weakly carcinogenic constituent of cigarette smoke, may be involved as a causative factor for the mutations frequently observed in the p53 tumor suppressor gene in lung cancer in smokers. Biomarkers are needed to further assess the possi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556963/ https://ncbi.nlm.nih.gov/pubmed/17559234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700075y |
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