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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
The current goal of diabetes therapy is to reduce time-averaged mean levels of glycemia, measured as HbA1c, to prevent diabetic complications. However, HbA1c only explains <25% of the variation in risk of developing complications. Because HbA1c does not correlate with glycemic variability when ad...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556800/ https://ncbi.nlm.nih.gov/pubmed/18809715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081188 |
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