Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication.

An adenovirus mutant, Ad2ts111, has previously been shown to be temperature sensitive for viral DNA replication in vivo and also to induce degradation of cellular DNA. Soluble nuclear extracts prepared from Ad2ts111-infected HeLa cells grown at either the permissive (32 degrees C) or the nonpermissi...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Stillman, B W, White, E, Grodzicker, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6368865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.2.598-605.1984
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