Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication.
An adenovirus mutant, Ad2ts111, has previously been shown to be temperature sensitive for viral DNA replication in vivo and also to induce degradation of cellular DNA. Soluble nuclear extracts prepared from Ad2ts111-infected HeLa cells grown at either the permissive (32 degrees C) or the nonpermissi...
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| Publicado no: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6368865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.2.598-605.1984 |
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