Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication.

An adenovirus mutant, Ad2ts111, has previously been shown to be temperature sensitive for viral DNA replication in vivo and also to induce degradation of cellular DNA. Soluble nuclear extracts prepared from Ad2ts111-infected HeLa cells grown at either the permissive (32 degrees C) or the nonpermissi...

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Pubblicato in:	J Virol
Autori principali:	Stillman, B W, White, E, Grodzicker, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6368865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.2.598-605.1984
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