Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire

The linker for activation of T cells (LAT) and the linker for activation of B cells (LAB/NTAL/LAT2) are integral proteins in receptor coupling to downstream events. Both proteins are expressed in natural killer (NK) cells and LAT is phosphorylated during target cell interactions or ligation of the i...

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Detalhes bibliográficos
Main Authors: Whittaker, Gillian C., Burshtyn, Deborah N., Orr, Selinda J., Quigley, Laura, Hodge, Deborah L., Pascal, Véronique, Zhang, Weiguo, McVicar, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556622/
https://ncbi.nlm.nih.gov/pubmed/18645037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-121590
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