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Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction

Mitochondrial diseases due to mutations in mitochondrial DNA can no longer be ignored in most medical areas. With prevalence certainly higher than one in 6000, they probably represent the most common form of metabolic disorders. Despite progress in identification of their molecular mechanisms, littl...

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Bibliografiske detaljer
Main Authors: Ellouze, Sami, Augustin, Sébastien, Bouaita, Aicha, Bonnet, Crystel, Simonutti, Manuel, Forster, Valérie, Picaud, Serge, Sahel, Jose-Alain, Corral-Debrinski, Marisol
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556433/
https://ncbi.nlm.nih.gov/pubmed/18771762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.08.013
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