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Limitations of allotopic expression of mitochondrial genes in mammalian cells.

The possibility of expressing mitochondrial DNA-coded genes in the nuclear-cytoplasmic compartment provides an attractive system for genetic treatment of mitochondrial disorders associated with mitochondrial DNA mutations. In theory, by recoding mitochondrial genes to adapt them to the universal gen...

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Detalhes bibliográficos
Main Authors: Oca-Cossio, Jose, Kenyon, Lesley, Hao, Huiling, Moraes, Carlos T
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462783/
https://ncbi.nlm.nih.gov/pubmed/14573482
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