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Techniques and Pitfalls in the Detection of Pathogenic Mitochondrial DNA Mutations

Mutations in the mitochondrial DNA (mtDNA) are now recognized as major contributors to human pathologies and possibly to normal aging. A large number of rearrangements and point mutations in protein coding and tRNA genes have been identified in patients with mitochondrial disorders. In this review,...

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Detalhes bibliográficos
Main Authors: Moraes, Carlos T., Atencio, David P., Oca-Cossio, Jose, Diaz, Francisca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907336/
https://ncbi.nlm.nih.gov/pubmed/14573777
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