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Polymorphism of human telomeric quadruplex structures
Human telomeric DNA consists of tandem repeats of the sequence d(TTAGGG). Compounds that can stabilize the intramolecular DNA G-quadruplexes formed in the human telomeric sequence have been shown to inhibit the activity of telomerase and telomere maintenance, thus the telomeric DNA G-quadruplex has...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556180/ https://ncbi.nlm.nih.gov/pubmed/18373984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2008.02.026 |
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