Structural and energetic analysis of activation by a cyclic nucleotide binding domain

MlotiK1 is a prokaryotic homolog of cyclic nucleotide-dependent ion channels which contains an intracellular C-terminal cyclic nucleotide binding domain (CNB domain). X-ray structures have been solved of the CNB domain in the absence of ligand and bound to cAMP. Both the full-length channel and CNB...

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Hlavní autoři: Altieri, Stephen L., Clayton, Gina M., Silverman, William R., Olivares, Adrian O., De La Cruz, Enrique M., Thomas, Lise R., Morais-Cabral, João H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555981/
https://ncbi.nlm.nih.gov/pubmed/18619611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.011
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