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Exon Loss Accounts for Differential Sorting of Na-K-Cl Cotransporters in Polarized Epithelial Cells

The renal Na-K-Cl cotransporter (NKCC2) is selectively expressed in the apical membranes of cells of the mammalian kidney, where it is the target of the clinically important loop diuretics. In contrast, the “secretory” NKCC1 cotransporter is localized in the basolateral membranes of many epithelia....

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Detalhes bibliográficos
Main Authors: Carmosino, Monica, Giménez, Ignacio, Caplan, Michael, Forbush, Biff
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555935/
https://ncbi.nlm.nih.gov/pubmed/18667527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0478
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