Sites of Regulated Phosphorylation that Control K-Cl Cotransporter Activity

Modulation of intracellular chloride concentration ([Cl(−)](i)) plays a fundamental role in cell volume regulation and neuronal response to GABA. Cl(−) exit via K-Cl cotransporters (KCCs) is a major determinant of [Cl(−)](I); however, mechanisms governing KCC activities are poorly understood. We ide...

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Autors principals: Rinehart, Jesse, Maksimova, Yelena D., Tanis, Jessica E., Stone, Kathryn L., Hodson, Caleb A., Zhang, Junhui, Risinger, Mary, Pan, Weijun, Wu, Dianqing, Colangelo, Christopher M., Forbush, Biff, Joiner, Clinton H., Gulcicek, Erol E., Gallagher, Patrick G., Lifton, Richard P.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811214/
https://ncbi.nlm.nih.gov/pubmed/19665974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.031
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