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DNA methylation inhibits the transfecting activity of replicative- form phi X174 DNA.

Replacement of virtually all the cytosine residues with 5-methylcytosine residues in the complementary strand of the replicative form (RF) of phi X174 DNA caused a 300- to 500-fold loss in its transfecting activity. Similar results were obtained with analogously methylated M13 RF. Transfection exper...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Wang, R Y, Shenoy, S, Ehrlich, M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1984
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.49.3.674-679.1984
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