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DNA methylation inhibits the transfecting activity of replicative- form phi X174 DNA.

Replacement of virtually all the cytosine residues with 5-methylcytosine residues in the complementary strand of the replicative form (RF) of phi X174 DNA caused a 300- to 500-fold loss in its transfecting activity. Similar results were obtained with analogously methylated M13 RF. Transfection exper...

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Detalles Bibliográficos
Main Authors: Wang, R Y, Shenoy, S, Ehrlich, M
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC255523/
https://ncbi.nlm.nih.gov/pubmed/6321756
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