DNA methylation inhibits the transfecting activity of replicative- form phi X174 DNA.
Replacement of virtually all the cytosine residues with 5-methylcytosine residues in the complementary strand of the replicative form (RF) of phi X174 DNA caused a 300- to 500-fold loss in its transfecting activity. Similar results were obtained with analogously methylated M13 RF. Transfection exper...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.49.3.674-679.1984 |
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