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A robust linear regression based algorithm for automated evaluation of peptide identifications from shotgun proteomics by use of reversed-phase liquid chromatography retention time

BACKGROUND: Rejection of false positive peptide matches in database searches of shotgun proteomic experimental data is highly desirable. Several methods have been developed to use the peptide retention time as to refine and improve peptide identifications from database search algorithms. This report...

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Detalhes bibliográficos
Main Authors: Xu, Hua, Yang, Lanhao, Freitas, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553802/
https://ncbi.nlm.nih.gov/pubmed/18713471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-347
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