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Mechanistic insights from reversible splicing catalysis

Recent work demonstrating the ability of spliceosomes purified after the second catalytic step of splicing to efficiently reverse both steps of the reaction provides answers to several unresolved questions regarding the splicing reaction, and raises many more.

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Detalles Bibliográficos
Autores principales: Smith, Duncan J., Konarska, Maria M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553733/
https://ncbi.nlm.nih.gov/pubmed/18755832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1289808
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