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Mechanistic insights from reversible splicing catalysis

Recent work demonstrating the ability of spliceosomes purified after the second catalytic step of splicing to efficiently reverse both steps of the reaction provides answers to several unresolved questions regarding the splicing reaction, and raises many more.

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Detalhes bibliográficos
Main Authors: Smith, Duncan J., Konarska, Maria M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553733/
https://ncbi.nlm.nih.gov/pubmed/18755832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1289808
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