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A manganese-dependent ribozyme in the 3′-untranslated region of Xenopus Vg1 mRNA
The smallest catalytic RNA identified to date is a manganese-dependent ribozyme that requires only a complex between GAAA and UUU to effect site-specific cleavage. We show here that this ribozyme occurs naturally in the 3′-UTR of Vg1 and β-actin mRNAs. In accord with earlier studies with model RNAs,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553595/ https://ncbi.nlm.nih.gov/pubmed/18753150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn530 |
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