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A manganese-dependent ribozyme in the 3′-untranslated region of Xenopus Vg1 mRNA

The smallest catalytic RNA identified to date is a manganese-dependent ribozyme that requires only a complex between GAAA and UUU to effect site-specific cleavage. We show here that this ribozyme occurs naturally in the 3′-UTR of Vg1 and β-actin mRNAs. In accord with earlier studies with model RNAs,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kolev, Nikolay G., Hartland, Emilia I., Huber, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553595/
https://ncbi.nlm.nih.gov/pubmed/18753150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn530
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