Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription

During secondary immunoglobulin (Ig) diversification in vertebrates, the sequence of the variable region of Ig genes may be altered by templated or non-templated mechanisms. In both cases, cytidine deamination by activation-induced cytidine deaminase (AID) in the transcribed Ig loci leads to DNA les...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mierau, Maren, Drexler, Guido A., Kutzera, André, Braunschmidt, Kerstin, Ellwart, Joachim, Eckardt-Schupp, Friederike, Fritz, Eberhard, Bachl, Jürgen, Jungnickel, Berit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553578/
https://ncbi.nlm.nih.gov/pubmed/18757891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn542
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados