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Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
The enzyme ribonucleotide reductase, responsible for the synthesis of deoxyribonucleotides (dNTP), is upregulated in response to DNA damage in all organisms. In Saccharomyces cerevisiae, dNTP concentration increases ∼6- to 8-fold in response to DNA damage. This concentration increase is associated w...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553575/ https://ncbi.nlm.nih.gov/pubmed/18772226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn555 |
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