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Endogenous kappa-opioid receptor systems inhibit hyperalgesia associated with localized peripheral inflammation

Peripheral inflammation evokes functional and biochemical changes in the periphery and spinal cord which result in central sensitization and hypersensitivity. Inhibitory control systems from the rostral ventromedial medulla (RVM) are also activated. The present study investigates whether endogenous...

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Detalhes bibliográficos
Main Authors: Schepers, R.J., Mahoney, Janet Lynn, Gehrke, Brenda Jean, Shippenberg, Toni Shaun
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553515/
https://ncbi.nlm.nih.gov/pubmed/18355964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.01.023
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