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Kappa Opioid Receptors on Dopaminergic Neurons Are Necessary for Kappa-Mediated Place Aversion

Kappa-opioid receptor (KOR) agonists have dysphoric properties in humans and are aversive in rodents. This has been attributed to the activation of KORs within the mesolimbic dopamine (DA) system. However, the role of DA in KOR-mediated aversion and stress remains divisive as recent studies have sug...

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Detalhes bibliográficos
Main Authors: Chefer, Vladimir I, Bäckman, Cristina M, Gigante, Eduardo D, Shippenberg, Toni S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828533/
https://ncbi.nlm.nih.gov/pubmed/23921954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.171
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