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Kappa Opioid Receptors on Dopaminergic Neurons Are Necessary for Kappa-Mediated Place Aversion

Kappa-opioid receptor (KOR) agonists have dysphoric properties in humans and are aversive in rodents. This has been attributed to the activation of KORs within the mesolimbic dopamine (DA) system. However, the role of DA in KOR-mediated aversion and stress remains divisive as recent studies have sug...

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Bibliografiske detaljer
Main Authors: Chefer, Vladimir I, Bäckman, Cristina M, Gigante, Eduardo D, Shippenberg, Toni S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828533/
https://ncbi.nlm.nih.gov/pubmed/23921954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.171
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