Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

Pore-forming toxins (PFTs) constitute the single largest class of proteinaceous bacterial virulence factors and are made by many of the most important bacterial pathogens. Host responses to these toxins are complex and poorly understood. We find that the endoplasmic reticulum unfolded protein respon...

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Main Authors: Bischof, Larry J., Kao, Cheng-Yuan, Los, Ferdinand C. O., Gonzalez, Manuel R., Shen, Zhouxin, Briggs, Steven P., van der Goot, F. Gisou, Aroian, Raffi V.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553261/
https://ncbi.nlm.nih.gov/pubmed/18846208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000176
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