Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

Pore-forming toxins (PFTs) constitute the single largest class of proteinaceous bacterial virulence factors and are made by many of the most important bacterial pathogens. Host responses to these toxins are complex and poorly understood. We find that the endoplasmic reticulum unfolded protein respon...

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Auteurs principaux: Bischof, Larry J., Kao, Cheng-Yuan, Los, Ferdinand C. O., Gonzalez, Manuel R., Shen, Zhouxin, Briggs, Steven P., van der Goot, F. Gisou, Aroian, Raffi V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553261/
https://ncbi.nlm.nih.gov/pubmed/18846208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000176
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