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RAB-5 and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin

Pore-forming toxins (PFTs) secreted by pathogenic bacteria are the most common bacterial protein toxins and are important virulence factors for infection. PFTs punch holes in host cell plasma membranes and although cells can counteract the resulting membrane damage, the underlying mechanisms at play...

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Detalhes bibliográficos
Main Authors: Los, Ferdinand C. O., Kao, Cheng-Yuan, Smitham, Jane, McDonald, Kent L., Ha, Christine, Peixoto, Christina A., Aroian, Raffi V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057397/
https://ncbi.nlm.nih.gov/pubmed/21320697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.01.005
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