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Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans

Reactive oxygen species (ROS) are generated by mitochondrial respiration and can react with and damage cellular components. According to the free radical theory of aging, oxidative damage from mitochondrial ROS is a major cause of cellular decline during aging. Mitochondrial uncoupling proteins (UCP...

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Detalhes bibliográficos
Main Authors: Iser, Wendy B., Kim, Daemyung, Bachman, Eric, Wolkow, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553218/
https://ncbi.nlm.nih.gov/pubmed/15893362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2005.04.002
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