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Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans

Reactive oxygen species (ROS) are generated by mitochondrial respiration and can react with and damage cellular components. According to the free radical theory of aging, oxidative damage from mitochondrial ROS is a major cause of cellular decline during aging. Mitochondrial uncoupling proteins (UCP...

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Bibliografiske detaljer
Main Authors: Iser, Wendy B., Kim, Daemyung, Bachman, Eric, Wolkow, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553218/
https://ncbi.nlm.nih.gov/pubmed/15893362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2005.04.002
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