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3′-Phosphoinositides Regulate the Coordination of Speed and Accuracy during Chemotaxis

The PI3K/PTEN pathway, as the regulator of 3′-phosphoinositide (3′-PI) dynamics, has emerged as a key regulator of chemoattractant gradient sensing during chemotaxis in Dictyostelium and other cell types. Previous results have shown 3′-PIs to be important for regulating basal cell motility and sensi...

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Bibliographic Details
Main Authors: Gruver, J. S., Wikswo, J. P., Chung, C. Y.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553113/
https://ncbi.nlm.nih.gov/pubmed/18676656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130179
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