The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration

Reorganization of the actin cytoskeleton is essential for cell motility and chemotaxis. Actin-binding proteins (ABPs) and membrane lipids, especially phosphoinositides PI(4,5)P(2) and PI(3,4,5)P(3) are involved in the regulation of this reorganization. At least 15 ABPs have been reported to interact...

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Publicat a:Br J Pharmacol
Autors principals: Wu, C-Y, Lin, M-W, Wu, D-C, Huang, Y-B, Huang, H-T, Chen, C-L
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Themed Section: Cytoskeleton, Extracellular Matrix, Cell Migration, Wound Healing and Related Topics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290701/
https://ncbi.nlm.nih.gov/pubmed/25420930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12777
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