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Role of RacC for the Regulation of WASP and Phosphatidylinositol 3-Kinase during Chemotaxis of Dictyostelium

WASP family proteins are key players for connecting multiple signaling pathways to F-actin polymerization. To dissect the highly integrated signaling pathways controlling WASP activity, we identified a Rac protein that binds to the GTPase binding domain of WASP. Using two-hybrid and FRET-based funct...

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Autors principals: Han, Ji W., Leeper, Laura, Rivero, Francisco, Chung, Chang Y.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853593/
https://ncbi.nlm.nih.gov/pubmed/16968699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605997200
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