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Rac regulation of chemotaxis and morphogenesis in Dictyostelium

Chemotaxis requires localized F-actin polymerization at the site of the plasma membrane closest to the chemoattractant source, a process controlled by Rac/Cdc42 GTPases. We identify Dictyostelium RacB as an essential mediator of this process. RacB is activated upon chemoattractant stimulation, exhib...

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Main Authors: Park, Kyung Chan, Rivero, Francisco, Meili, Ruedi, Lee, Susan, Apone, Fabio, Firtel, Richard A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC524383/
https://ncbi.nlm.nih.gov/pubmed/15470506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600368
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