Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

OBJECTIVE—Sulforaphane is an activator of transcription factor NF-E2–related factor-2 (nrf2) that regulates gene expression through the promoter antioxidant response element (ARE). Nrf2 regulates the transcription of a battery of protective and metabolic enzymes. The aim of this study was to assess...

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Main Authors: Xue, Mingzhan, Qian, Qingwen, Adaikalakoteswari, Antonysunil, Rabbani, Naila, Babaei-Jadidi, Roya, Thornalley, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2008
Assuntos:
Complications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551693/
https://ncbi.nlm.nih.gov/pubmed/18633117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db06-1003
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