Nitrones Reverse Hyperglycemia-Induced Endothelial Dysfunction in Bovine Aortic Endothelial Cells

Hyperglycemia has been implicated in the development of endothelial dysfunction through heightened ROS production. Since nitrones reverse eNOS dysfunction, increase antioxidant enzyme activity, and suppress pro-apoptotic signaling pathway and mitochondrial dysfunction from ROS-induced toxicity, the...

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Publicado no:Biochem Pharmacol
Main Authors: Headley, Colwyn A., DiSilvestro, David, Hemann, Craig, Bryant, Kelsey E., Chen, Chun-Aun, Das, Amlan, Ziouzenkova, Ouliana, Durand, Grégory, Villamena, Frederick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248535/
https://ncbi.nlm.nih.gov/pubmed/26774452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.01.005
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