Alterations in MicroRNA Expression Contribute to Fatty Acid–Induced Pancreatic β-Cell Dysfunction

OBJECTIVE—Visceral obesity and elevated plasma free fatty acids are predisposing factors for type 2 diabetes. Chronic exposure to these lipids is detrimental for pancreatic β-cells, resulting in reduced insulin content, defective insulin secretion, and apoptosis. We investigated the involvement in t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lovis, Pascal, Roggli, Elodie, Laybutt, D. Ross, Gattesco, Sonia, Yang, Jiang-Yan, Widmann, Christian, Abderrahmani, Amar, Regazzi, Romano
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2008
Matèries:
Islet Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551683/
https://ncbi.nlm.nih.gov/pubmed/18633110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1252
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars