Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic β-Cells

OBJECTIVE: Pancreatic β-cells exposed to proinflammatory cytokines display alterations in gene expression resulting in defective insulin secretion and apoptosis. MicroRNAs are small noncoding RNAs emerging as key regulators of gene expression. Here, we evaluated the contribution of microRNAs to cyto...

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Bibliographic Details
Main Authors: Roggli, Elodie, Britan, Aurore, Gattesco, Sonia, Lin-Marq, Nathalie, Abderrahmani, Amar, Meda, Paolo, Regazzi, Romano
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844845/
https://ncbi.nlm.nih.gov/pubmed/20086228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0881
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