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Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides.

Six mutants isolated from herpes simplex virus type 1 were judged to be defective with respect to the virion-associated function acting to rapidly shut off host polypeptide synthesis in herpes simplex virus-infected cells. The mutants were capable of proper entry into the cells, but, unlike the pare...

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Autors principals: Read, G S, Frenkel, N
Format: Artigo
Idioma:Inglês
Publicat: 1983
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC255152/
https://ncbi.nlm.nih.gov/pubmed/6302315
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