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Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides.

Six mutants isolated from herpes simplex virus type 1 were judged to be defective with respect to the virion-associated function acting to rapidly shut off host polypeptide synthesis in herpes simplex virus-infected cells. The mutants were capable of proper entry into the cells, but, unlike the pare...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Read, G S, Frenkel, N
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1983
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6302315/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.46.2.498-512.1983
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