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Solid-State NMR Spectroscopy Reveals That Water is Nonessential to the Core Structure of Alpha-Synuclein Fibrils

Protein aggregation is implicated in the etiology of numerous neurodegenerative diseases. An understanding of aggregation mechanisms is enhanced by atomic-resolution structural information, of which relatively little is currently available. Lewy bodies, the pathological hallmark of Parkinson’s disea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kloepper, Kathryn D., Hartman, Kevin L., Ladror, Daniel T., Rienstra, Chad M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551327/
https://ncbi.nlm.nih.gov/pubmed/17985869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp077036z
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