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Genetic variability of herpes simplex virus: development of a pathogenic variant during passaging of a nonpathogenic herpes simplex virus type 1 virus strain in mouse brain.

Herpes simplex virus type 1 ANG (HSV-1 ANG) is originally nonpathogenic for inbred mice upon intraperitoneal intravenous, or intravaginal inoculation. In contrast, mice died of encephalitis within 4 to 5 days after intracerebral inoculation with this strain. HSV-1 ANG was serially passaged in mouse...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Kaerner, H C, Schröder, C H, Ott-Hartmann, A, Kümel, G, Kirchner, H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1983
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.46.1.83-93.1983
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