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Presence of markers for virulence in the unique short region or repeat region or both of pseudorabies hybrid viruses.

The unique short region and part of the repeat region of virulent pseudorabies virus strain NIA-3 was replaced by the corresponding region of the avirulent NIA-4 strain by transfection with subgenomic DNA fragments. The resulting hybrid virus showed a reduced virulence in both mice and pigs. Therefo...

詳細記述

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書誌詳細
主要な著者: Berns, A, van den Ouweland, A, Quint, W, van Oirschot, J, Gielkens, A
フォーマット: Artigo
言語:Inglês
出版事項: 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC254982/
https://ncbi.nlm.nih.gov/pubmed/2981366
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