Presence of markers for virulence in the unique short region or repeat region or both of pseudorabies hybrid viruses.

The unique short region and part of the repeat region of virulent pseudorabies virus strain NIA-3 was replaced by the corresponding region of the avirulent NIA-4 strain by transfection with subgenomic DNA fragments. The resulting hybrid virus showed a reduced virulence in both mice and pigs. Therefo...

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Main Authors: Berns, A, van den Ouweland, A, Quint, W, van Oirschot, J, Gielkens, A
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC254982/
https://ncbi.nlm.nih.gov/pubmed/2981366
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