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The Cdc6 Nucleotide–Binding Site Regulates Its Activity in DNA Replication in Human Cells

The Cdc6 protein of budding yeast and its homologues in other species play an essential role in the initiation of DNA replication. A cDNA encoding a human homologue of Cdc6 (HsCdc6) has been cloned and expressed as a fusion protein in a soluble and functionally active form. The purified protein boun...

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Detaylı Bibliyografya
Asıl Yazarlar: Herbig, Utz, Marlar, Clinton A., Fanning, Ellen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC25495/
https://ncbi.nlm.nih.gov/pubmed/10436018
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