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The Cdc6 Nucleotide–Binding Site Regulates Its Activity in DNA Replication in Human Cells

The Cdc6 protein of budding yeast and its homologues in other species play an essential role in the initiation of DNA replication. A cDNA encoding a human homologue of Cdc6 (HsCdc6) has been cloned and expressed as a fusion protein in a soluble and functionally active form. The purified protein boun...

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Autors principals: Herbig, Utz, Marlar, Clinton A., Fanning, Ellen
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC25495/
https://ncbi.nlm.nih.gov/pubmed/10436018
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