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Development of tRNA synthetases and connection to genetic code and disease

The genetic code is established by the aminoacylation reactions of aminoacyl tRNA synthetases, where amino acids are matched with triplet anticodons imbedded in the cognate tRNAs. The code established in this way is so robust that it gave birth to the entire tree of life. The tRNA synthetases are or...

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Dettagli Bibliografici
Autore principale: Schimmel, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548368/
https://ncbi.nlm.nih.gov/pubmed/18765819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037242.108
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